Hexamidine diisocyanate (Hexamidine diisethionate, CAS 659-40-5) is a white hygroscopic crystalline powder, a mild broad-spectrum cationic antimicrobial agent. It has good antibacterial and antifungal effects, formaldehyde-free, widely used in sensitive skincare, anti-acne, anti-dandruff shampoo and personal care preservatives. TNJ Chemical is the leading manufacturer and exporter since 2001. We guarantee high quality, competitive price, stable supply, fast delivery and tech support etc. To inquire more, please contact sales@tnjchem.com
Product Information
CAS No.: 659-40-5
Synonyms: Hexamidine diisethionate, Hexamidine di(2-hydroxyethanesulfonate)
Molecular Formula: C₂₄H₃₈N₄O₁₀S₂Molecular Weight: 606.72
EINECS: 211-533-5
INCI: Hexamidine Diisethionate
Appearance: white to slight off-white powder
Solubility: sparingly soluble in cold water, soluble in hot water and propylene glycol, slightly soluble in ethanol, insoluble in oils
pH (aqueous solution): 3.5–6.0 recommended working range
Characteristic: hygroscopic, low irritation, formaldehyde releaser free, stable in cosmetic formulations
Quality Specification
| Item | Cosmetic / Pharma Grade |
|---|---|
| Assay (HPLC) | ≥99.0% |
| Loss on drying | ≤5.0% |
| Heavy Metal (Pb) | ≤10 ppm |
| Arsenic (As) | ≤2 ppm |
| Related impurities | ≤0.50% |
Use & Application
Skincare: anti-acne, anti-inflammatory active for facial lotion, toner and sensitive skin care
Hair care: anti-dandruff agent for shampoo, inhibits Malassezia
Personal care: preservative for intimate wash, baby care and oral care products
Pharmaceutical: topical antiseptic for skin and mucosal preparations
Packaging & Storage
Package: 1kg / 5kg aluminium foil bag, 25kg paper drum or plastic drum
Store in cool, dry, shaded warehouse, keep sealed and protect from moisture


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