Where to Buy N,N-Dicyclohexylcarbodiimide CAS 538-75-0 China origin from top professional China N,N-Dicyclohexylcarbodiimide suppliers, factory & manufacturers with reliable quality. If you want to find good N,N-Dicyclohexylcarbodiimide price, please mail to sales@tnjchem.com
N,N-Dicyclohexylcarbodiimide is white crystal or slightly yellow transparent liquid. Melting point 35-36°C, boiling point 154-156°C (1.47kPa), 98-100°C (66.7kPa). It is soluble in benzene, ethanol, ether, but insoluble in water.
Specification
Application
Mainly used for the condensation of amino acids in the artificial synthesis of peptides. For example, in Fmoc-solid phase synthesis, the carboxyl group of an amino acid forms an amide bond with the amino group of another amino acid. In order to make the carboxyl group more susceptible to attack by nucleophiles, the negatively charged oxygen atom needs to be activated by Chemicalbook to become a better leaving group. DCC plays this role. The oxygen atom of the carboxyl group on the amino acid acts as a nucleophile to attack the carbon atom in the middle of the DCC molecule to combine DCC with the carboxyl group to form an ester structure, making the nucleophilic attack of the amino group easier
25 kg/drum
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